Hey crypto enthusiasts, if you're keeping an eye on the intersection of AI and blockchain, you won't want to miss the latest scoop from 0xJeff, a seasoned DeFi expert and former Spartan Group member. In a buzzworthy tweet that's already racking up likes and reposts, he dropped his top picks for DeAI (decentralized AI), DeFi (decentralized finance), DeFAI (a blend of DeFi and AI), straight-up AI, and agent-based projects heading into September 2025. These aren't just random shouts—these are projects with real catalysts, adoption potential, and ecosystem-building power that could influence everything from trading bots to meme token narratives.

For those new to the lingo, DeAI refers to decentralized artificial intelligence systems that run on blockchain, making AI more accessible and trustless without relying on big tech giants. DeFi is the world of financial services on the blockchain, like lending and trading without banks. And AI agents? Think autonomous software that can execute tasks, like trading or predicting markets, often powered by smart contracts. 0xJeff's list is packed with projects that could spark the next meme-worthy hype cycles, especially as AI tools start generating viral content and trading strategies for meme tokens.

Here's a breakdown of his top recommendations, with simple explanations to help you get why they're worth watching:

• ​Flock.io​: Tagged as having the most catalysts in any DeAI project this season. Flock is building a decentralized network for AI model training and inference, potentially lowering costs and democratizing AI access—which could lead to more AI-driven meme creation tools.

• Bittensor: Dubbed the "#1 DeAI/Darwinian AI ecosystem" and "The AI Bitcoin." This is a decentralized machine learning protocol where nodes compete to provide the best AI models, rewarded with TAO tokens. It's like evolution for AI, and its community-driven approach often spawns meme-like excitement in crypto circles.

• ​Pendle Finance​: Singlehandedly scaling on-chain interest rate markets. Pendle lets users trade and tokenize future yields from DeFi assets, making it easier to hedge or speculate on rates. In a volatile market, this could stabilize meme token plays by offering yield farming opportunities.

• ​Giza Tech​: Leading the DeFi x AI narrative with real-world adoption. Giza focuses on verifiable AI computations on blockchain, ensuring AI outputs are tamper-proof—perfect for trust-sensitive apps like AI-powered meme token analytics.

• ​Almanak​: Showing initial product-market fit with agents plus smart contracts for scalable DeFAI. This project aims to automate DeFi strategies using AI agents, which could supercharge automated trading in meme tokens.

• ​Cod3x​: The top end-to-end AI trading co-pilot. It's designed to assist traders with AI insights, potentially spotting meme token pumps before they happen.

• ​OpenServ AI​: Like a Web3 version of YC (Y Combinator) mixed with workflow automations and n8n (an open-source automation tool). This could foster startups building AI tools for meme communities.

• ​CreatorBid​: Version 2 is set to surface quality agents, with three or more products launching soon. It's a marketplace for AI agents, which might include fun, meme-generating bots.

• ​Michael Tao​: The #1 incubator on something called CB^ (possibly a platform or chain), plus an AIxBT engine for the Bittensor ecosystem. Incubators like this often birth viral meme projects.

• ​Billy Bets​, ​Aion5100​, ​Sire Agent​: A trio of AI x Prediction Markets agents. These use AI to bet on outcomes, which could tie into meme token events like celebrity endorsements or viral trends.

• ​Comput3 AI​: Top-tier compute for everyone, including distributed training. This infrastructure play supports AI development, indirectly boosting AI-enhanced meme ecosystems.

One reply captured the vibe perfectly: "The 'De's' are strong with this one. September FOMO activated." And they weren't kidding—check out this fun visual that sums up the excitement:

The tweet sparked conversations, with users asking about Pendle's long-term dominance in rate markets and suggesting additions like Infinit Labs or Velvet Capital. It's clear the community is hyped, and for good reason—these projects could drive the next narrative in crypto, where AI agents handle everything from meme token launches to automated trades.

If you're intrigued and want the deep dive on the theses behind these picks, head over to 0xJeff's newsletter on Substack, where he's dropping more from "The After Hour" series this weekend. At Meme Insider, we're watching how these DeAI advancements could turbocharge meme token creativity and trading—think AI-generated memes or agent-predicted pumps. Stay tuned for more updates, and remember, always DYOR (do your own research) before diving in!