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Top DEX Volumes in September 2025: Uniswap Leads the Meme Token Trading Surge

Top DEX Volumes in September 2025: Uniswap Leads the Meme Token Trading Surge

If you're deep into the world of meme tokens, you know that decentralized exchanges (DEXs) are where the action happens. These platforms let you swap tokens without intermediaries, and they're ground zero for launching and trading the latest viral memes. A recent tweet from @AIAdoptHQ on X (formerly Twitter) dropped a fresh chart highlighting the top DEXs by 24-hour volume as of September 10, 2025, sourced from DefiLlama. Let's break it down and see what it means for meme token enthusiasts.

Bar chart showing top DEX volumes in 24 hours, with Uniswap at $3.3B leading the pack

Uniswap Still Reigns Supreme

Right at the top, Uniswap clocks in with a whopping $3.3 billion in daily volume. Built on Ethereum, Uniswap has long been a favorite for meme token launches thanks to its user-friendly interface and massive liquidity pools. If you've ever snagged a hot new meme like PEPE or DOGE derivatives early, chances are you did it here. Its dominance shows that despite competition, Ethereum's ecosystem remains a powerhouse for DeFi and memes.

PancakeSwap Holds Strong on Binance Smart Chain

Coming in second is PancakeSwap at $2.2 billion. Operating on the Binance Smart Chain (BSC), this DEX offers lower fees and faster transactions, making it a go-to for budget-conscious traders. Meme tokens thrive here because of the ease of creating and listing new assets—perfect for those quick pumps and community-driven hype cycles.

Solana DEXs Are Stealing the Spotlight

Look further down the list, and you'll see a bunch of Solana-based DEXs making waves. Meteora at $990 million, Raydium at $586 million, Orca at $527 million, and Pump at $296 million highlight Solana's growing role in the meme token space. Solana's high-speed, low-cost network is ideal for the fast-paced trading that memes demand. Platforms like Pump.fun have revolutionized meme launches, allowing anyone to create a token in seconds and tap into instant liquidity.

Hyperliquid and Aerodrome are the rising stars mentioned in the tweet, with $709 million and $681 million respectively. Hyperliquid focuses on perpetual futures, which could tie into leveraged bets on meme tokens, while Aerodrome on the Base chain (an Ethereum layer-2) brings optimistic rollups for even smoother trades.

What This Means for Meme Token Traders

This snapshot reveals a heating "DEX wars," as the tweet puts it. With fresh liquidity flowing into newer platforms, meme token creators and traders have more options than ever. If you're building or investing in memes, keep an eye on these volumes—they signal where the community's attention (and money) is going. Higher volumes mean better liquidity, tighter spreads, and more opportunities for those viral gains.

For blockchain practitioners, this data underscores the importance of cross-chain awareness. Tools like DefiLlama are essential for tracking these metrics in real-time. Whether you're optimizing for fees on BSC or speed on Solana, understanding DEX dynamics can supercharge your strategy.

As the crypto landscape evolves, memes aren't just jokes anymore—they're a serious part of DeFi. Stay tuned to Meme Insider for more updates on how these trends shape the token economy. What's your favorite DEX for meme hunting? Drop a comment below!

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