In the fast-paced world of crypto, staying ahead means spotting the next big trend before it explodes. That's exactly what Defi0xJeff, a seasoned DeFi expert and former Spartan Group member, is doing in his popular newsletter series, The After Hour. His latest episode, EP21, dropped on September 21, 2025, and it's all about the brewing "DeAI szn" – that's decentralized AI season for those new to the lingo.

Jeff shared his insights via a tweet, quoting his previous EP20 to draw parallels. Back in October-November 2024, we saw the groundwork for "Agent szn," where AI agents started making waves in automation and decision-making on the blockchain. Now, in September 2025, Jeff senses a similar setup for DeAI, blending decentralized finance (DeFi) with artificial

- 記事では、Defi0xJeffがいかにDeAIシーズンの土台を強調しているかについて論じることができます。​
intelligence in ways that could revolutionize how we interact with crypto ecosystems.

Understanding DeAI: Decentralized AI Explained

If you're scratching your head over DeAI, think of it as AI that's not controlled by big tech giants like Google or OpenAI. Instead, it's powered by blockchain networks, ensuring transparency, security, and no single point of failure. Decentralized AI allows for verifiable computations, where AI models run on distributed nodes, and results can be trusted without a central authority. This is huge for crypto because it opens doors to AI-driven trading, predictive analytics, and even autonomous agents that handle your portfolio.

In simpler terms, DeAI makes AI more democratic. Projects in this space often use blockchain to incentivize data providers, model trainers, and validators with tokens, creating a self-sustaining economy. It's not just hype – it's solving real problems like data privacy and bias in traditional AI.

Catalysts Fueling the DeAI Boom

Jeff breaks down the catalysts in EP21, pointing to recent developments that are setting the stage. From my vantage point at Meme Insider, where we track how these trends intersect with meme tokens, here's what stands out based on current market signals.

First, major exchanges are listing DeAI tokens, signaling mainstream adoption. For instance, DeAgentAI (AIA) is gearing up for a launch on Binance Alpha and Futures, focusing on secure, verifiable AI interactions across blockchains. This could spark volatility and interest in related meme plays.

Second, infrastructure upgrades are accelerating. The Ethereum Foundation's new dAI team is building an AI economy directly on Ethereum, which might boost Layer-2 solutions and AI-integrated DeFi protocols. Imagine AI agents optimizing yields in vaults or predicting meme token pumps – that's the kind of innovation we're talking about.

Third, broader market trends like the convergence of AI and crypto are gaining traction. A Forbes piece predicts 2025 as the year DeAI shines, with tangible results beyond hype. Add in upcoming launches like Autonomys Network's $AI3 token on major exchanges, and you've got a recipe for explosive growth.

Jeff's Theses and Plays: What to Watch

While the full details are behind a paywall in Jeff's Substack, he teases two key theses or plays in DeAI. Drawing from industry buzz, these likely involve AI DeFi vaults and financial agents, as hinted in his EP20. Think projects like 0G Labs, which is pioneering crypto-AI integration, or OORT, that's grabbing spotlight in altcoin season with DeAI focus.

For meme token enthusiasts, DeAI could supercharge community-driven projects. AI agents might automate meme creation, launch fair pumps on platforms like pump.fun (mentioned in EP20), or even predict viral trends. Keep an eye on AI-themed memes that tie into these launches – they often ride the wave of bigger narratives.

Upcoming DeAI Launches to Get Excited About

Jeff highlights upcoming launches he's bullish on, and the crypto space is buzzing with options. Here are a few standouts:

• DeAgentAI: Set for Binance integration, this project emphasizes scalable AI agents on blockchain. Perfect for DeFi automation.

• Autonomys ($AI3)​: Launching on Kraken, KuCoin, and MEXC, it's enhancing accessibility for decentralized AI tools.

• OORT: With recent price surges, it's positioning as a DeAI leader, potentially influencing meme ecosystems through data-driven insights.

Other notables include emerging projects from CoinMarketCap's upcoming list, where DeAI features prominently. For deeper dives, check Tangem's top AI crypto coins for 2025.

Why This Matters for Meme Tokens and Blockchain Practitioners

At Meme Insider, we see DeAI as a game-changer for meme tokens. Traditional memes thrive on hype, but DeAI introduces smart agents that could analyze sentiment, automate trades, or even generate meme content on-chain. This blends fun with function, helping practitioners build more resilient portfolios.

Jeff's call to "Make Sunday Count" is a reminder to dive in now. Whether you're a DeFi degen or a meme hunter, DeAI szn could be your ticket to the next bull run. Subscribe to his newsletter for the full scoop, and stay tuned to meme-insider.com for how these trends play out in the meme world.